Project Review

نویسندگان

  • G. Cairo
  • M. Minunni
چکیده

The reliable determination of human recombinant erythropoietin (rhEpo) abuse to enhance the athletic performance is an important problem for sport and represents a continuous challenge for investigators involved in anti-doping. The analytical tests used to detect rhEpo in urines are often inadequate and suffer from many interfering factors. Hepcidin, a liver-derived peptide which is the major regulator of body iron metabolism, is an accurate indicator of changes in blood levels of Epo. Indeed, Epo administration in humans caused a marked reduction in urinary and circulating hepcidin.

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تاریخ انتشار 2011